Peptide Storage & Handling: Stability, Temperature & Shelf Life
Consistent storage and careful handling are essential to maintain peptide integrity. This practical guide covers temperature ranges, reconstitution, and shelf life, so you can protect quality from delivery to final use.
1) Lyophilized vs. Reconstituted
Lyophilized (dry) peptides are generally more stable than reconstituted solutions. Keep vials closed, dry and protected from light. Once reconstituted, peptides become more sensitive to temperature, pH and contamination, so storage windows are shorter.
2) Temperature Guidelines
- Short term (days–weeks): Refrigerated storage (2–8 °C) is common for lyophilized peptides.
- Long term (months): Freezer storage (≤−20 °C) is often preferred. Avoid frost-free cycles that fluctuate temperature.
- After reconstitution: Keep refrigerated and use promptly according to the product guidance and batch lab report.
Tip: Minimise freeze–thaw events. If you expect multiple uses, aliquot the solution into small sterile volumes and freeze once.
3) Reconstitution Basics
- Use only the recommended diluent (see label or independent lab report).
- Let the vial reach fridge temperature before opening to reduce condensation.
- Gently swirl—avoid vigorous shaking that can denature sensitive sequences.
- Record reconstitution date and planned discard date.
4) Shelf Life & Stability
Stability depends on the sequence, purity, diluent and storage. As a general rule, lyophilized peptides stored cold and dry can remain stable for extended periods, while reconstituted solutions should be used within a much shorter window. Always consult the third-party lab test for batch-specific guidance.
5) Handling & Lab Hygiene
- Work on a clean surface with sterile accessories.
- Limit exposure to air, light and room temperature.
- Label vials clearly (batch, concentration, dates).
- Dispose according to local guidelines.
Transparency & Research Use
GenPep provides batch-level transparency to support quality and trust. For policy context, see Research-Use-Only and how we approach independent lab testing. To learn more about GLP-1 peptides, read our articles on Semaglutide and Wegovy.
FAQ
Should peptides be stored in a fridge or freezer?
Lyophilized peptides are often refrigerated for short term; for long-term stability, a freezer (≤−20 °C) is commonly preferred. Avoid repeated freeze–thaw cycles.
How long do reconstituted peptides last?
They are more sensitive than dry peptides. Keep refrigerated and use promptly as advised by the product guidance and lab report.
What diluent should I use?
Only the diluent recommended for that batch (see label or lab report). Using the wrong diluent can affect pH, solubility and stability.